Dietary curcumin supplementation regulates the lipid metabolism in laying hens

This study was conducted to investigate the effects of dietary curcumin on hepatic lipid metabolism and antioxidant capacity in Roman laying hens. A total 144 hens (28 weeks old) were allocated 4 treatments that included at concentrations 0, 50, 150, 250 mg/kg for 9 weeks. Each treatment had 6 replicates per group with replicate (2 birds/cage). The results showed supplementation decreased (P < 0.05) absolute relative abdominal fat weight during 32–34 wk. Curcumin supplemented 150 been reduced triglycerides (TG) cholesterol plasma, liver TG concentrations, enzyme activities malic (ME) lipoprotein lipase throughout experiment. also mRNA expression Sterol expression-regulatory protein-1c (SREBP-1c), ACC, FAS, ME while it increased Apolipoprotein B-100 Apolipoprotein-II. Further research found boosted activity enzymes Superoxide dismutase, Catalase, Glutathione peroxidase plasma liver. It lowered levels Malondialdehyde In conclusion, inclusion regulated metabolism, deposition improved HighlightsCurcumin can regulate by reducing liver.Curcumin genes involved synthesis